Coming Together for PD Research

As a study participant there is no guarantee that you will receive any benefits from being in this study. However, the information gathered through your participation may help researchers learn new things about the investigational drug, which could potentially benefit future generations of people affected by PD.

The study doctor and study team are helping to conduct the Tempo Studies as part of their commitment to advancing potential treatment options for PD. What comes first, however, is their commitment to you – and to helping you make a choice that’s right for you.

All eligible study participants will receive at no cost:

  • Study-related consultation and care
  • Study visits, tests, assessments, and procedures
  • Study drugs (investigational drug or placebo)

In addition, reimbursement for travel-related expenses (e.g., gas, parking, tolls) may also be available. Speak to a member of the study team for more details.

Study participation will take approximately 35 weeks.

Screening Period – UP TO 4 WEEKS

The study doctor and study staff will review your medical history and conduct a number of tests and be asked questions to determine if you are fully eligible to participate. This visit will last approximately four hours.
Study Treatment Period 27 WEEKS

You will begin taking your assigned study drug (investigational drug or placebo) as directed by the study doctor. You will be asked to attend ten study visits where you will take part in study- related tests and be asked questions to monitor your health and the effects (if any) of your assigned study drug. These visits are expected to last approximately one to two hours.

Who is Eligible to Participate?
You may be eligible to participate in the Tempo Studies if you meet the following criteria:

  • Have been diagnosed with PD
  • Currently taking Levodopa
  • 40 to 80 years of age
  • Have never received deep brain stimulation treatment

Tavapadon is an investigational drug being evaluated for treatment of PD. It is a dopamine receptor agonist designed to target a specific dopamine receptor in the brain that the Sponsor believes may help reduce PD symptoms that affect your movement and daily activities. The Sponsor believes tavapadon may also have less potential to cause some of the side effects commonly associated with currently approved dopamine agonists, which target different types of dopamine receptors.

Each of the Tempo Studies will compare the investigational drug to placebo. A placebo is an inactive material, such as a sugar pill, that looks like the investigational drug, but does not contain any active drug. Placebos play an important role in clinical research studies, as they help researchers determine if an investigational drug works better or is safer than taking nothing.

Participants in the Tempo Studies will be randomly assigned (like flipping a coin) to receive the investigational drug or placebo. Your chances of receiving the investigational drug or placebo will depend on which of the three Tempo Studies you are participating in. Neither you nor the study doctor will know if you are receiving the investigational drug; however, the study doctor can find out this information if he or she feels it is necessary for your health.

For additional information about the study drug, please speak with a member of the study staff.

1 Step 1

Join The Study

No Insurance Required - No Cost to Patient

  • Qualified participants will receive investigational medication and study-related medical care at no cost
  • Participants may also receive compensation for time and travel
  • No health insurance required and no overnight stays
To learn more and see all active clinical research studies, please visit our Active Studies page or contact our Research Team.
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If your child or teenager suffers from migraines, they may qualify for our clinical trial studying a new potential treatment.

Our Pediatric Migraine Clinical Trial
Biohaven Pharmaceuticals is studying an investigational medication, called rimegepant, for the acute treatment of migraines in the pediatric population. If your child is between 12 and 17 years of age and has at least a 6-month history of migraine, they may qualify.

The study will last approximately 58 weeks, and all participants will receive the investigational medication, plus all study-related assessments and healthcare, at no cost for up to the entire term of the study.
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Health insurance is not required to take part in this study. Compensation for participation and reimbursement for transportation to and from clinics may also be provided.
Some clinics may have extended evening and weekend hours to accommodate working parents, teens and participant schedules.

1 Step 1

Join The Study

No Insurance Required - No Cost to Patient

  • Qualified participants will receive investigational medication and study-related medical care at no cost
  • Participants may also receive compensation for time and travel
  • No health insurance required and no overnight stays
To learn more and see all active clinical research studies, please visit our Active Studies page or contact our Research Team.
keyboard_arrow_leftPrevious
Nextkeyboard_arrow_right

Who is this study for?

Teens may qualify for this study if they meet the following criteria:

  • Between the ages of 12 and 17
  • Have at least 1 migraine per month
  • Have at least a 6-month history of migraine

The migraine study clinicians will further assess medical and migraine history to determine eligibility.

Participants will receive:

  • The investigational medication at no cost for up to 58 weeks.
  • All study-related healthcare and evaluations at no cost for up to 58 weeks

In addition:

  • Compensation for participation may be provided
  • Reimbursement for transportation to and from clinics may also be provided
  • Health insurance not required to participate


A migraine can cause severe throbbing pain or a pulsing sensation, usually on just one side of the head. It’s often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Headaches can vary between from being a minor aggravation to a severe and incapacitating pain. It can be difficult to identify whether an individual is suffering from a mild headache or a migraine, which is a neurological disease, affecting 38 million men, women and children in the United States. Consequently, it is essential to emphasize the distinction between a migraine and a headache as it leads to rapid relief with effective treatments. Fresno migraine specialist Dr Bhatia’s Neuro Pain Medical Center located on Bullard Ave, Fresno is conducting an advanced clinical research study on migraine attacks.

A headache is in which blood vessels constrict and dilate, thus releasing inflammatory substances that cause painful pulsations. A chronic headache is accompanied by mild to severe pain commonly occurring on both sides of the head for more than four hours on more than 15 days per month. Assertive initial treatment coupled with continuing management may well reduce pain and result in fewer headaches in the future. Conversely, a migraine headache is the outcome of definite physiologic changes that take place within the brain and result in distinctive pain with the combined symptoms.

 

SUBMIT ONLINE APPLICATION FOR MIGRAINE STUDY NOW

Migraines often begin in childhood, adolescence or early adulthood. Migraines may progress through four stages: prodrome, aura, headache and post-drome, though you may not experience all stages.
One or two days before a migraine, you may notice subtle changes that warn of an upcoming migraine, including:

• Constipation
• Mood changes, from depression to euphoria
• Food cravings
• Neck stiffness
• Increased thirst and urination
• Frequent yawning

The most common migraine symptoms are:

• Throbbing, pulsating pain – 85 percent
• Light sensitivity – 80 percent
• Sound sensitivity – 76 percent
• Nausea – 73 percent
• Pain on one side – 59 percent
• Vision changes, blurred vision – 44 percent
• Aura – 36 percent
• Vomiting – 29 percent
(Note: These figures are from the American Migraine Study II of almost 4,000 migraine sufferers in 1999)

Fresno Migraine Specialist Dr. Bhatia has Treatment options:

As a matter of fact, most of the people will encounter a headache sooner or later in their lives. However, there are people who deal with more lasting and severe headaches and migraines than others. The Neurologist Dr. Bhatia based in Fresno, CA offers top notch medical care for neurological conditions and also recruits patients for migraine study and research.

You can also apply to qualify for a free Migraine-based research study. The goal of clinical trials is to determine if a new test or treatment works and is safe. The advanced studies done during clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. If you are experiencing migraines or know a friend or family with migraine issues, you can refer them to our clinic.

The center offers a wide-ranging treatment to patients suffering with chronic headache and migraine in Fresno, CA. You will get the right help at the right time with the Neuro Pain Medical Center’s online available team catering to appointments, referrals, RX refills, and clinical trials.

Fresno migraine specialist Dr Bhatia
Fresno migraine specialist Dr Bhatia

This website is for informational purposes only. Please dial 911 for emergency.

Parkinson's Tempo 3 Study
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