Categories: Research
Author
Research Team
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Categories: Research

Author

Research Team

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Changes in behavior are some of the more difficult Alzheimer’s symptoms to deal with.

Alzheimer’s disease is a progressive disease that slowly destroys nerve cells in the brain which affect memory and thought processes, resulting in a continuing decline in performing daily activities. It is characterized by non-cognitive, behavioral, or psychiatric symptoms, which are seen in 90% of individuals with dementia.

Agitation is a behavioral condition that people with any type of dementia can experience. For individuals with the type of dementia caused by Alzheimer’s disease, agitation is quite common, with over half of patients experiencing it.

Common symptoms of agitation may include:

  • Restlessness
  • Verbal or physical aggressiveness
  • Emotional distress
  • Irritability
  • Wandering

Individuals with agitation associated with Alzheimer’s disease may also become upset easily, resist help, appear uncooperative, and act in a stubborn or disruptive manner which can be very upsetting to families.

The purpose of this clinical research study is to test how well Masupirdine (SUVN-502) treats agitation associated with dementia of the Alzheimer’s type, learn about the safety of the study drug, and see how well you or your loved one tolerate(s) a once-a-day oral dose.

The total duration of the clinical research study for participants, including screening, is about 20 weeks and includes 7 visits.

Each participant and caregiver will take part in a screening period of up to 4 weeks, followed by the treatment period of 12 weeks, and conclude with a follow up visit at week 16.

Who is Eligible to Participate in this Clinical Research Study?

To qualify, you or a loved one must:

  • Be at least 50 years old.
  • Have been diagnosed with Alzheimer’s disease.
  • Have agitation associated with Alzheimer’s disease.
  • Have a caregiver or study partner willing to attend all study visits.

There are additional clinical research study requirements to participate. A study representative will discuss them with you.